France-Spain High Speed connects 21 cities with four separate routes.
Paris to/from Barcelona
- TGV EuroDuplex trains operate from Paris to Barcelona
- 2 daily round-trips year-round, 3-4 daily round-trips from June to September
- Best travel time 6h 19m
Lyon to/from Barcelona
- AVE S-100 trains operate from Lyon to Barcelona.
- 1 daily round-trip year-round
- Best travel time 4h 55m
Marseille to/from Madrid
- AVE S-100 trains operate from Marseille to Barcelona/Madrid.
- 1 daily round-trip year-round
- Best travel time 7h 40m
Toulouse to/from Barcelona
- TGV EuroDuplex trains operate from Toulouse to Barcelona.
- 1 daily round-trip from Mar 24 to Sep 25
- Best travel time 3h 12m
All trains stop at Perpignan on the French side and at Figueres, Girona and Barcelona on the Spanish side.
The Madrid-Marseille route also stops at Aix en Provence, Avignon, Tarragona and Zaragoza; while Lyon to Barcelona also stops at Valence.
Timetables for 2019 and 2020 are available here.